Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites

J Med Chem. 2003 Jun 5;46(12):2261-70. doi: 10.1021/jm0204237.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Acrylates / metabolism
  • Acrylates / pharmacology
  • Acrylates / therapeutic use
  • Angiotensin II / metabolism*
  • Angiotensin Receptor Antagonists*
  • Animals
  • Antihypertensive Agents / metabolism*
  • Antihypertensive Agents / pharmacology
  • Antihypertensive Agents / therapeutic use
  • Benzimidazoles / metabolism
  • Benzimidazoles / pharmacology
  • Benzimidazoles / therapeutic use
  • Biphenyl Compounds / metabolism
  • Biphenyl Compounds / pharmacology
  • Biphenyl Compounds / therapeutic use
  • Growth Hormone / analogs & derivatives
  • Growth Hormone / pharmacology
  • Growth Hormone / therapeutic use
  • Humans
  • Hypertension / drug therapy
  • Hypertension / metabolism
  • Imidazoles / metabolism
  • Imidazoles / pharmacology
  • Imidazoles / therapeutic use
  • Irbesartan
  • Losartan / metabolism
  • Losartan / pharmacology
  • Losartan / therapeutic use
  • Models, Molecular
  • Receptor, Angiotensin, Type 1
  • Tetrazoles / metabolism
  • Tetrazoles / pharmacology
  • Tetrazoles / therapeutic use
  • Thiophenes*
  • Thromboxane A2 / antagonists & inhibitors
  • Thromboxane A2 / metabolism

Substances

  • Acrylates
  • Angiotensin Receptor Antagonists
  • Antihypertensive Agents
  • Benzimidazoles
  • Biphenyl Compounds
  • Imidazoles
  • Receptor, Angiotensin, Type 1
  • Tetrazoles
  • Thiophenes
  • Angiotensin II
  • eprosartan
  • Thromboxane A2
  • Growth Hormone
  • Irbesartan
  • Losartan
  • candesartan